By analyzing the correlation between the ADAM17 gene and immune invasion scores in 9,555 tumor samples from 39 cancer species, we observed a significant correlation between the expression of this gene and immune invasion in 21 cancer species, with 7 (GBMLGG, COAD, COADREAD, KIPAN, READ, PAAD, DLBC) positive and 14 (CESC, ESCA, STES, KIRP, UCEC, HNSC, LUSC, THYM, THCA, SKCM-M, SKCM, TGCT, SKCM-P, ACC) negative correlations (Figure 5). Here, ADAM17 is linked to cancer.