Besides, we collected ADAM17 gene and 60 immune checkpoint regulatory genes, 150 immune regulatory genes (41 chemokines, 18 receptors, 21 MHCs, 24 immunoinhibitors, 46 immunostimulators) and 64 tumor-related immune cells for immune checkpoint genetic analysis, immunomodulatory gene analysis, immune cell analysis, and immune invasion analysis, respectively. Here, ADAM17 is linked to neoplasm.