The results of the forest plot showed that the TP53, SPOP, MYO9A, SSPO, FAT2, IGSF10, KIF13A, XIRP2, MUC17, NALCN, PIK3CA, and MUC16 genes were significantly different mutant genes in the KIF2C high and low expression groups in PCa (Figure 5D). The gene discussed is SPOP; the disease is posterior cortical atrophy.