The autophagy in PCa induced by CHRM1 was summarized with a model, which activates the AMPK/mTOR pathway by linking the Gq protein, acts on Atg5 and other autophagy-related genes, and induces autophagy, thereby enhancing the migration and invasion ability of tumor cells (Figure 6(e)). This evidence concerns the gene CHRM1 and posterior cortical atrophy.