SOX9 and age-related macular degeneration: To explore the mechanism of LCN2 in CNV-induced AMD, potential transcription factors were predicted through the KnockTF and CistromeDB databases, and AMD-related transcription factor SOX9 was obtained after the intersection analysis with the 2015 and 1334 DEGs obtained from the GSE29801 and GSE103060 datasets, respectively (Figures 2(a)–2(c)).