To explore the mechanism of LCN2 in CNV-induced AMD, potential transcription factors were predicted through the KnockTF and CistromeDB databases, and AMD-related transcription factor SOX9 was obtained after the intersection analysis with the 2015 and 1334 DEGs obtained from the GSE29801 and GSE103060 datasets, respectively (Figures 2(a)–2(c)). Here, LCN2 is linked to age-related macular degeneration.