MLKL and metabolic dysfunction-associated steatohepatitis: Neither the specific inhibitor of programmed necrosis nor the knockout of the mixed lineage kinase domain-like protein MLKL could inhibit cell death, while the ferroptosis inhibitors trolox and DFO inhibited cell death in a methionine-/choline-deficient (MCD), ethionine-supplemented (CDE) diet-induced NASH mouse model, suggesting that the ferroptosis pathway is activated in the liver of NASH mice (Tsurusaki et al., 2019).