A feature of PASC patients with POTS-like symptoms is a high prevalence of specific circulating autoantibodies, including G-protein-coupled receptor (GPCR) antibodies (such as adrenergic, muscarinic and angiotensin II type-1 receptors) and the ganglionic neuronal nicotinic acetylcholine receptor (g-AChR) (75). This evidence concerns the gene AGTR1 and postural orthostatic tachycardia syndrome.