The 4D measurement of the HCCDB dataset showed that MCM6 was not a liver-specific gene (logFC = −1.58), and MCM6 were increased in HCC compared to normal liver tissue (logFC = 0.34) and corresponding paracancer tissue (logFC = 0.91) (Figure 1(c)). This evidence concerns the gene MCM6 and hepatocellular carcinoma.