Our results showed that PNRC1, ATF3, CD207, and CD1C were obviously reduced in the HCC samples compared to non-tumorous samples, whereas RFX3, USP11, USP34, PSMA3, PSMA4, CLEC4A, and CD1A were increased in HCC samples. The gene discussed is CLEC4A; the disease is hepatocellular carcinoma.