According to univariate analysis, the following relevant factors found to be associated with PD: tumor diameter (OR=12.06, p<0.0006), depth of invasion (cT stage) (OR=14.55, p=0.0006), lymph node metastases (cN stage) (OR=5.89, p<0.0001), and serum tumor markers, including CEA (OR=2.50, p<0.0001), CA125 (OR=11.46, p<0.0001), CA72-4 (OR=4.09, p<0.0001), CA19-9 (OR=2.74, p<0.0001), CA50 (OR=5.20, p<0.0001) and CA242 (OR=3.83, p<0.0001). The gene discussed is MUC16; the disease is neoplasm.