MRPL13 expression is reduced in OXPHOS-deficient hepatoma cells (SNU354 and SNU423 cell lines), and the specific inhibition of mitochondrial glycosomal translation by siRNA-mediated knockdown of MRPL13 decreases expression of the OXPHOS complex IV subunit protein COX2 (26). This evidence concerns the gene MRPL13 and hepatocellular carcinoma.