Besides, according to a study (37) of Gu et al., lncRNA DMDRMR can bind to IGF2BP3 and enhance the activity of IGF2BP3 by the m6A-dependent manner in KIRC, which would stabilize the expression of target genes CDK4, COL6A1, LAMA5 and FN1 and promote the G1/S transition of RCC. The gene discussed is CDK4; the disease is renal cell carcinoma.