Prognosis analysis suggested that high expressions of ADM, ATP2B1, CCL20, EREG, GNAI3, IRAK2, MMP14, NAMPT, NMI, PCDH7, PLAUR, PVR, RELA, RIPK2, SERPINE1, SPHK1, TAPBP, and TPBG were correlated with poor overall survival and tumor stage in LUAD. The gene discussed is PVR; the disease is neoplasm.