SPHK1 and lung cancer: Additionally, we found that these genes (ADM, ATP2B1, EREG, NMI, PCDH7, PLAUR, PVR, RELA, RIPK2, SERPINE1, SPHK1) correlated with poor disease-specific survival (DSS) in lung cancer (Figure 3A), high expression of CCL20, EREG, NAMPT, NMI, PCDH7, PVR, SERPINE1, and SPHK1 correlated with poor progression-free survival in patients with lung cancer and high expression of CCL20, NMI, and PVR associated with poor disease-free survival (DFS) in patients with lung cancer (Figures 3B, C).