Prognosis analysis suggested that high expressions of ADM, ATP2B1, CCL20, EREG, GNAI3, IRAK2, MMP14, NAMPT, NMI, PCDH7, PLAUR, PVR, RELA, RIPK2, SERPINE1, SPHK1, TAPBP, and TPBG were correlated with poor overall survival and tumor stage in LUAD. Here, IRAK2 is linked to neoplasm.