HSF1 and neoplasm: The 15 ferroptosis-related genes (NRAS, TFAP2C, SLC2A8, BRD4, FADS2, IFNG, WIPI1, SLC2A12, MT1G, GABARAPL1, DUOX1, FH, CISD1, SLC1A5, HSF1), which were included in the prognostic prediction model, most have been reported to regulate tumor progression through pathways such as cell energy metabolism, protein transport, and immune response etc. NRAS is an oncogene which encodes a GTPase.