Patients with MetS were significantly older (P=0.04), more likely to have a history of coronary heart disease (CHD) (P=0.002); had a higher Charlson Comorbidity Index (CCI) (P<0.001), a lower estimated Glomerular filtration rate(eGFR) (P=0.014), and lower AST/ALT ratio (P<0.001). The gene discussed is GPT; the disease is metabolic syndrome.