Five KEGG pathways of target genes (OAS family and the top 50 co-expression genes) in the pathogenesis of pancreatic cancer were identified by Metascape, including ko05164 (Influenza A), hsa04621 (NOD-like receptor signaling pathway), hsa04622 (RIG-I-like receptor signaling pathway), hsa04612 (Antigen processing and presentation), and ko05133 (Pertussis) (Figure 11 and Supplementary Table 3). Here, SMOC1 is linked to pertussis.