Since HPV infection is suspected to contribute to the emergence of other cancer types (Bladder Urothelial Carcinoma (BLCA), HNSC, Colon adenocarcinoma (COAD), Prostate Adenocarcinoma (PRAD)), an HPV-associated pan cancer analysis of IKZF3, FOXP3, and JAK3 was performed. The gene discussed is JAK3; the disease is polyarteritis nodosa.