Since HPV infection is suspected to contribute to the emergence of other cancer types (Bladder Urothelial Carcinoma (BLCA), HNSC, Colon adenocarcinoma (COAD), Prostate Adenocarcinoma (PRAD)), an HPV-associated pan cancer analysis of IKZF3, FOXP3, and JAK3 was performed. Here, JAK3 is linked to bladder transitional cell carcinoma.