Via the gut-lung axis, mucorale specific T cells (the CD4+ and CD8+ cells) interact with the gut microflora, which determines the overall functionality of the immune system, it's therefore important to maintain the gut microbiome intact. In addition, excessive vitamin A supplementation to get rid of COVID-19 may impair the humoral immunity (antibody-mediated) which in turn enables the fungal growth in our body [11]. The gene discussed is CD4; the disease is COVID-19.