ACIN1 and COVID-19: Among the top Δβ-value methylation changes comparing pre- and post-COVID-19 time points, we observed two differentially methylated loci (cg02037503 and cg23712970) in a gene promoter transcription start site regulatory region of the apoptotic chromatin condensation inducer 1 (ACIN1) gene Supplementary Figure S2 that decreased in DNA methylation following COVID-19 by approximately 15% for both CpG sites (Figures 1D,E).