We downloaded three datasets for sepsis-induced ARDS from the GEO database and identified 9 DElncRNAs (ARRDC1-AS1, C3orf36, SCARNA10, SPATA13, TERC, TUG1, LINC01556, LINC02897, and LINC02915), 9 DEmiRNAs (hsa-miR-96, hsa-miR-101, hsa-miR-125b, hsa-miR-140, hsa-miR-149, hsa-miR-202, hsa-miR-320c, hsa-miR-326, and hsa-miR-429), and 269 DEmRNAs. The gene discussed is ARRDC1; the disease is acute respiratory distress syndrome.