Thirty-eight patients who diagnosed with neurogenetic disease had other neurologic or systemic manifestation, except three patients with variants in KCNA1, KMT2B, and TOR1A genes (Figure 4); The patient with the KCNA1 mutation had episodic ataxia alone, and those with the KMT2B or TOR1A mutations showed dystonia only. This evidence concerns the gene KMT2B and Familial paroxysmal ataxia.