PDC and obesity due to melanocortin 4 receptor deficiency: Arachidonic acid metabolism has a higher proportion in the PDC group, which is an unsaturated fatty acid, which entails risk for developing intestinal inflammation, obesity, type 1 diabetes, and alcoholic fatty liver (Leiva-Gea et al., 2018; Miyamoto et al., 2019; Mayr et al., 2020; Sun et al., 2020).