Therefore, this study was conducted to investigate whether Nab-PTX induced apoptosis of human gastric cancer cells (AGS) through the autophagy signaling pathway and compared the differences in autophagy expression and apoptosis of gastric cancer cells induced by Nab-PTX, 5-FU, LBP, and Nab-PTX + 5-Fu. This evidence concerns the gene LBP and gastric cancer.