The miR-149-3p target genes are involved in PI3K-Akt signaling pathway, Ras signaling pathway, AGE-RAGE signaling pathway in diabetic complications, focal adhesion, MAPK signaling pathway, proteoglycans in cancer, hypertrophic cardiomyopathy, cholinergic synapse, cocaine addiction, and protein digestion and absorption (Figure 8). This evidence concerns the gene RENBP and cocaine dependence.