PARP1 and cancer: This study investigated the function of the apoptosis‐inducing proteins, p‐53, Bcl‐2, Bax, cytochrome C, cleaved PARP‐1 and caspase‐3, and key cell survival proteins; p‐PI3K and p‐GSK3‐α/β, which reported high sensitivity to the treatment and improved anti‐cancer efficacy, and hence was introduced as a more promising therapeutic agent given its innervation of multiple immune/metabolic pathways.167