In comparison, gamma‐tocotrienol also possesses the capability for inducing autophagy as shown in breast cancer and prostate cancer cells in which it stimulated an increased Beclin‐2 and Bax/Bcl‐2 ratio, cleaved caspase 3, cleaved PARP, and diminished signaling of PI3K/AKT/mTOR activation that adds to anticancer properties of tocotrienol in inducing apoptosis and autophagy leading to tumor cell death (Figure 10).144, 145. This evidence concerns the gene PARP1 and prostate cancer.