Consistent with this, the metastatic nodule number, metastatic tumor weight, and ascites volume in mice bearing sh-Ct-OATP1B3-OVCAR3 cells significantly decreased, whereas that in mice bearing OE-Ct-OATP1B3-CAOV3 cells obviously increased, when compared to those of the respective control (Fig. 7C and D). The gene discussed is SLCO1B3; the disease is neoplasm.