CXCL12 and posterior cortical atrophy: In concordance with the concept that CXCR4/CXCL12 signaling triggers neovascularization in PCa TEC, we confirm that the CXCR4 antagonist AMD3100 efficiently reduces of the proliferative capacity of TEC (Fig. 8B) and efficiently represses elevated cell migration of TEC (Fig. 8C).