In RCC, the knocking down of DCLK1 via siDCLK1 transfection and its significant association with expression of EMT transcription factors SNAI1, SNAI2, TWIST1, ZEB1, and mesenchymal marker Vimentin protein demonstrated that inhibition of DCLK1 reduced the invasive and metastatic potential [23]. This evidence concerns the gene DCLK1 and renal cell carcinoma.