TPPP and chronic kidney disease: We found five such SNPs: (i) two in the UMOD-PDILT locus, which confirmed UMOD for a role in CKD-progression, (ii) three SNPs in novel loci for eGFR-decline, which mapped to three genes with eQTL in kidney tissue (GALNTL5 in PRKAG2 locus, kidney-tissue specific; SPATA7, and TPPP), making these compelling candidates as CKD-progression genes.