T CD8+ cell abundance, which can be estimated by MCP‐counter (Additional file 2: Figure S14–S16), CIBERSORT, EPIC (Additional file 2: Figure S17–S19) and quanTIseq algorithms, also significantly decreased in tumour samples, except for the HCCDB4 sample in MCP‐counter and CIBERSORT estimations, which showed no significant changes. Here, CD8A is linked to neoplasm.