TNFSF4 and neoplasm: In the presence of TILs and a low dose of the armed OVs, significantly increased killing of the tumor cells was observed compared with TIL and parental OV-Δ34.5 or OV in the absence of TILs (Figures 2G and S5B), suggesting that the killing of tumor cells was mediated by TILs and enhanced by the armed OV encoding OX40L and IL12.