CD86 and neoplasm: Treatment with OV-mOX40L/IL12 alone or in combination with autologous TIL therapy increased the expression of MHC I, MHC II, costimulatory ligands (CD86 and OX40L), and IL12 in a substantial percentage of the tumor cells, indicating the successful conversion of tumor cells into APC-like cells (Figures 5A, S10A, S11C, and S11E).