Finally, we analyzed the gene expression profiles of hPSC-derived populations (i.e., EB-CD144+, unsorted-BC, BC-CD144+CD45+ and ECs) by Affymetrix GeneChip microarrays and compared them to undifferentiated hPSCs, to differentiated-hPSCs themselves and to physiological subpopulations isolated from human embryonic livers (EL). The gene discussed is PTPRC; the disease is breast cancer.