A genome-wide association study (GWAS) of ILA identified four genome-wide significant variants (in FCF1P3, IPO11, HTR1E, MUC5B); while the MUC5B rs35705950 promoter polymorphism is well known in IPF, the other three loci were not associated with IPF. This evidence concerns the gene HTR1E and idiopathic pulmonary fibrosis.