We noted that when testing the associations of individual transcripts with ILA or death, 23 genes had a discordant direction of effect for ILA and 3 genes (HLA-DP1, HLA-DP2, LPAR6) had a discordant direction of effect for all-cause mortality compared to the directions of effects reported for the IPF score (Additional file 1: Table S1). This evidence concerns the gene LPAR6 and idiopathic pulmonary fibrosis.