Consistently most contributing factors from both methods (MCA and RFA) across both years was found to be knowledge of HIV status, being on ART, ART dosage, current CD4 cell count, perceived risk of contracting HIV, knowledge of HIV status, alcohol, total number of sex partners in the last 12 months, total number of lifetime sex partner, ever diagnosed of TB and exposure to TB in last 12 months. The gene discussed is CD4; the disease is tuberculosis.