The thyroid hormone sensitive protein (THRSP; Spot14; S14) is a nuclear protein, which is abundantly expressed in lipogenic tissues such as in liver, mammary gland, and adipose tissue (AT) and lipogenic breast cancers (Freake and Moon 2003; Freake and Oppenheimer 1987; Jump 1989; Jump et al. 1984). Here, THRSP is linked to breast carcinoma.