Targeting of EGFR [37, 38], HER2 [37, 38], PDGFR [39, 40] and immunosuppressive molecules [41] have been suggested as potential strategies from molecular studies of gynaecological carcinosarcomas; however, data are limited and the vast majority of data are derived from UCS, rather than OCS. The gene discussed is PDGFRB; the disease is carcinosarcoma.