Further protective associations included the expression of the ABCG subfamily member ABCG1 (logrank P = 5.4*10–6, HR 0.5, CI 0.37–0.68), ABCG2 (logrank P = 1.8*10–12, HR 0.35, CI 0.26–0.48) and ABCG5 (logrank P = 2.6*10–5, HR 0.48, CI 0.34–0.68) in ccRCC and HCC, as well as correlations of CFTR levels with improved outcomes in lung adenocarcinoma (logrank P = 3*10–5, HR 0.54 CI 0.41–0.73). Here, ABCG5 is linked to nonpapillary renal cell carcinoma.