Furthermore, expression of the orphan transporters ABCF3 and ABCF1 was increased with worse outcomes in HCC (logrank P = 4.4*10–5, HR 2.05, CI 1.44–2.92) and in BRCA patients undergoing endocrine therapy (logrank P = 9.6*10–7, HR 1.7, CI 1.37–2.11). This evidence concerns the gene ABCF3 and hepatocellular carcinoma.