TMPRSS2-ETS fusions, and TMPRSS2-ERG fusions specifically, were common in both BRCA2d and BRCA2i, but we did not identify a difference in the frequency of these events by BRCA2 status in either primary or metastatic tumors, as has been reported for germline BRCA2d prostate cancer7,35,36. Here, BRCA2 is linked to metastatic neoplasm.