SPOP and neoplasm: Pathogenic SNVs at PTEN (7.2%), SPOP (6.9%), KMT2C (5.8%), CSMD1 (5.7%), SYNE1 (5.7%), CSMD3 (5.7%), and FOXA1 (5.6%) were also present in ≥5% of primary BRCA2d tumors; however, these genes also did not differ in mutation frequency by tumor BRCA2 status after multiple testing correction.