TMPRSS2 and metastatic neoplasm: TMPRSS2-ETS fusions, and TMPRSS2-ERG fusions specifically, were common in both BRCA2d and BRCA2i, but we did not identify a difference in the frequency of these events by BRCA2 status in either primary or metastatic tumors, as has been reported for germline BRCA2d prostate cancer7,35,36.