AR and adenocarcinoma: Our HEC-1A-Sw71 attachment model profits from the luminal epithelium adenocarcinoma origin of the HEC-1A, defining them as epithelial, polarized cells with apical pole, expressing estrogen, progesterone, and androgen receptors and from the Sw71 spheroids’ imprint, closer to the developing embryo’s trophoblast22,33,36⁠.