USP11 and cancer: Yayu Huang et al. [79] identified that USP11 was upregulated in colorectal cancer and facilitated the proliferation and metastasis by regulating the stability of IGF2BP3, which was also found to be related to liver cancer [80, 81], pancreatic cancer [82] and ovarian cancer [83, 84], implying that USP11-IGF2B3 might regulate the progression of more cancers.