The percentage of CD8+ T cells (Figure 7J,K) and IFN‐γ+CD8+ activated T cells (Figure 7L) was slightly decreased by the enhanced radiotherapy of DDRi@CAT‐M0Exos + IR, but largely increased by DDRi@CAT‐M1Exos + IR and DDRi@CAT‐PD‐M1Exos + IR due to the remodeling of the suppressive tumor immune microenvironment. The gene discussed is CD8A; the disease is neoplasm.