CASP3 and infection: Consistently with the previous data, a temporal quantification of hiPS-NPCs by immunofluorescence with markers of proliferation and apoptosis indicated that ZIKVBr. infection caused significant decrease in phosphorylated histone H3 (pHH3; Figure 6J) and substantial increase in cleaved caspase 3 (cCASP3; Figure 6K) at DPI 3, but not at earlier time points.