Close examination of the GWAS SNPs in the HDAC9-associated CAD risk locus indicated that rs2107595 is the lead SNP (GWAS P value = 1.25 x 10−24) [13,14,16], although rs57301765 is in high LD with rs2107595 (r2 = 0.96 in Europeans) and has a similar GWAS P value (P = 2.81 x 10−23) (Fig 1A and 1B and Table 1) [13]. Here, HDAC9 is linked to coronary artery disorder.