Marfan syndrome is an autosomal dominant disease characterized by musculoskeletal and ocular abnormalities, and cardiovascular disease.[1] It is a disorder of the connective tissue proteins fibrillin-1 and transforming growth factor-β that leads to abnormal connective tissue in many organs.[5] Fibrillin is widely distributed in ocular connective tissue, as reflected by the myriad ocular abnormalities found in Marfan syndrome.[6] The axial myopia and often appeared bluish sclera in Marfan syndrome are postulated to occur due to the weakened, thinned sclera.[7,8]. Here, FBN1 is linked to cardiovascular disorder.