Importantly, treatments with SGKL repressed the increased levels of TNF‐α, IL‐1β, and IL‐6 in the colon, serum, and hippocampus in response to CRS stimulation in rats (Figure 2E, F1 = 27.12, p < 0.0001, F2 = 33.56, p < 0.0001, F3 = 21.97, p < 0.0001; Figure 2F, F1 = 34.99, p < 0.0001, F2 = 36.66, p < 0.0001, F3 = 48.26, p < 0.0001; Figure 2G, F1 = 14.98, p < 0.0001, F2 = 34.70, p < 0.0001, F3 = 21.52, p < 0.0001). The gene discussed is TNF; the disease is congenital rubella syndrome.