Over the last ten years, several works have demonstrated that different epigenetics enzymes such as histone acetyltransferases (HATs) and deacetylase (HDAC) play an important role not only in governing gene expression changes underlying cardiac diseases,10 but also in regulating cell energy metabolism, affecting enzymes of glycolysis, glucose oxidation, electron transport chain and fatty acid β‐oxidation.11 Here, HDAC9 is linked to heart disorder.