While, Liu et al. suggested that YSSXG Chinese medicine may have a protective effect against thalassemia via inhibiting the formation of alpha-globin-cytotoxic precipitates in erythrocytes by upregulating GATA-1 transcription factor and alpha-hemoglobin stabilizing protein (AHSP) (Liu et al., 2006). The gene discussed is GATA1; the disease is thalassemia.