ACE2 and lung disorder: These findings show that A/J mice develop both a SARS-like pulmonary disease and subsequent multi-organ failure when inoculated with MHV-1 intranasally, despite these two coronaviruses using different receptors, angiotensin-converting enzyme 2 (ACE2) and carcinoembryonic antigen-related cell adhesion molecule 1 (CEACAM1) (SARS-CoV-2 and MHV-1, respectively).