Research groups, including ourselves, have used hiPSCs derived from patients with SNCA multiplication mutations to model synucleinopathies (Byers et al., 2011; Devine et al., 2011; Flierl et al., 2014; Oliveira et al., 2015; Lin et al., 2016; Prots et al., 2018; Chen et al., 2019; Brazdis et al., 2020). The gene discussed is SNCA; the disease is synucleinopathy.