RUNX1 and acute lymphoblastic leukemia: That patients with t(12;21)/ETV6:RUNX1 had significantly less foster clones, and a higher maximum number of evolved clones could confirm results obtained in 2004 by Hübner et al. on t(12;21)/ETV6:RUNX1 BCP-ALL, who found that t(12;21)/ETV6:RUNX1 BCP-ALL had a higher number of Ig/TCR rearrangements but with lower IgH oligoclonality (38).