PAK1 and malignant colon neoplasm: This enrichment analysis showed that those co-expressed genes were involved in the TGF-beta pathway, pathways in liver cancer, pathways in renal cell cancer, pathways in clear cell renal cell cancer, integrated breast cancer pathway, computational model of aerobic glycolysis, metabolic reprogramming in colon cancer, RAC1/PAK1/p38/MMP2 pathway, and glycolysis and gluconeogenesis (Figure 3C).